TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes

Dr. Braden Tierney joins us to discuss gene-level metagenomic architectures across diseases that yield high-resolution microbiome diagnostic indicators. 

 

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this Ask the Expert podcast we talk with Carmen Valcarce PhD and Klara Klein MD PhD from VTV Therapteutics. We discuss TTP399 development as an adjunct therapy to insulin in patients with Type 1 Diabetes.

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

 

Topic: What are the most promising approaches for beta cell replacement moving forward?

Anchors: Doug Melton PhD (HSCI), Ali Naji MD PhD (PENN), Mike Rickles MD (PENN), Felicia Pagliuca PhD (Vertex) Matthias Hebrok PhD, (UCSF)

Panel: Jon Odorico MD (U Wisc), Pete Butler MD (UCLA) Cherie Stabler, PhD (UF), Mark Atkinson, PhD (UF), Ekaterine Bershivili MD PhD (UGeneva)

WHAT: State of the Science is an interactive conversation with room for granular and lively debate focused on the most pressing issues in type 1 diabetes (T1D) research. Our goal is to foster open science, interaction, and collaboration–all hallmarks of the(sugar)science mission.

These virtual conversations will involve: 

30 minute introduction – What’s HOT in this field? Describing the state of the art.

20 minute panel interface – What does the future hold?

10 minutes – Audience Q/A WHO: Anchors (2) – introduce the topic, state of the art, and what’s happening in the field Panelists (3) – debate current hypotheses and postulate what the future folds

Audience (50-100) – contribute meaningful questions and insights

Link to our page: https://thesugarscience.org/state-of-...

Dr. Jessica Kenison joins us to discuss re-balancing the immune system and introducing antigen-specific immune tolerance to treat T1D.

Dr. Jessica Kennison is a Postdoctoral Research Fellow at Brigham and Women's Hospital and Scientist at AnTolRx, Inc.

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this episode, Dr. Teresa Mastracci joins us to discuss the exocrine pancreas in T1D; is it a player, or merely a spectator? 

Dr. Mastracci is an Assistant Professor in Biology at Indiana University. In 2017 she was named one of the top Ten Under 40 up & coming stars in Biopharma Research and Business by Genetic Engineering News and was recognized as one of the Indianapolis Business Journal’s Forty Under 40.

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this episode, Dr. Elliot Botvinick joins us to talk about his work with multi-analyte sensing and insulin infusion at UCI. Tune in to hear about iGLOBE. 

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this episode, Dr. Andrew Wang, Dr. Kin Man Au, and Dr. Roland Tisch from the University of North Carolina join us to discuss their recent work, including the recent publication, "Immune Checkpoint-Bioengineered Beta Cell Vaccine Reverses Early-Onset Type 1 Diabetes". 

 

Full paper link: https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202101253

 

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this episode, Dr. Jonathan Weissman joins us in our Ask the Expert format to discuss genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. 

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this episode, Rob Screaton joins us to discuss one major question: Can we get adult human beta cells to regenerate?

His lab uses high-throughput functional genomic imaging screens to identify novel players involved in cell signaling pathways that control human pancreatic beta cell proliferation. In addition, we are interested in the function and quality control of mitochondria, critical subcellular organelles essential for cell function and survival.

This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

 

In this episode re-release, Avnesh Thakor joins us to discuss bioscaffolds that are used to support pancreatic islet transplantation. Dr. Thakor's research interests are focused primarily on the pancreas, with respect to regenerative medicine and oncology. In Thakor's lab, they are creating biocompatible 3D structures which contain spaces to accommodate islets. These bioscaffolds will aim to facilitate oxygen generation and angiogenesis, both of which are essential for islet survival and function.       

Click on this link to learn more about the lab. 

https://med.stanford.edu/thakorlab/Pancreas.html