TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes

In this episode, Professor Matthias Barth joins us to discuss his work studying higher education at Leuphana University in Germany. Dr. Barth is one of the steering-group members of the Postdoc Academy for Transformational Leadership, a training programme for researchers in the sustainability field. 

In this episode, David Wagner joins us to present and answer questions on his work at the University of Colorado and with Op-T-Mune. This episode is in our Ask the Expert style: 

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

In this episode, Eiji Yoshihara joins us to discuss the research taking place at Yoshihara Lab at the Lundquist Institute. The overarching goal of the Yoshihara Lab is to understand the origins of life and physiology through utilizing state-of-the-art biomedical technologies.

Japanese Translation @ minute 25

Learn more about the Yoshihara Lab Here

In this episode, Dr. Toby Coates joins us to give us some insights into his work with the Biodegradable Temporizing Matrix (BTM). 

In this episode, Matthieu Raoux joins us to talk about his fascinating research at the University of Bordeaux, France. Dr. Raoux provides insights to his recent publication: Dynamic Uni- and Multicellular Patterns Encode Biphasic Activity in Pancreatic Islets.

" Our data provide a new uni- and multicellular model of islet β-cell activation: during the 1st phase, small but highly active β-cell clusters are dominant, whereas during the 2nd phase electrical coupling generates large functional clusters via multicellular slow potentials to favor an economic sustained activity."

 

Checkout his latest publication!

In this episode, Professor Noel G. Morgan joins us to discuss his work in cellular pharmacology and studying the pathophysiology of pancreatic beta-cells in diabetes. He also talks about his work with B cells and a recent publication, "Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to “B” or Not to “B”: Is That Still the Question?". 

Link to his paper: https://www.frontiersin.org/articles/10.3389/fendo.2021.617437/full

In this episode, we speak with Alok Joglekar about his fantastic research at the University of Pittsburg. Dr. Joglekar provides us with some insights to his publication: T cell antigen discovery. T cells play a critical role in the elimination of pathogens and the surveillance of pathological cells.

 

Read the full text here

In this episode, Dr. Matthias von Herrath joins us to discuss his work at the La Jolla Institute for Immunology and at pharmaceutical company Novo Nordisk. He discusses one of his recently published papers, "Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial". 

Full paper link: https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00019-X/fulltext 

In this episode, we speak to Dr. Hans Sollinger, MD, PhD, Founder & Interim CSO of Endsulin. Dr. Sollinger has been a leader in diabetes care for decades and has revolutionized the field twice. 

 

Endsulin is overcoming the limitations of today's taxing diabetes treatments with a patented gene construct and simple process that re-engineers part of the liver, allowing it to produce and regulate insulin on its own.

Learn more about Endsulin here!

In this episode, Burcak Yesildag joins us to discuss her work in the Islet Solutions Group at InSphero, generating advanced and high-throughput compatible assays and disease models for diabetes drug discovery. She also gives us some insight into a recent publication, "Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes". 

Full paper: Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes

To learn more about InSphero: https://insphero.com/