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Welcome to TheSugarScience Podcast where our mission is to highlight and connect researchers in the type 1 diabetes space. The(sugar)science is an interactive digital platform founded to curate the scientific conversation among type 1 diabetes (T1D) researchers. Our goal is to expedite a cure for T1D by promoting collaboration across diverse research disciplines.
Episodes
Tuesday Dec 15, 2020
Episode 44: Julie Sneddon, PhD, Assistant Professor, UCSF School of Medicine
Tuesday Dec 15, 2020
Tuesday Dec 15, 2020
In this episode, Julie Sneddon joins us to discuss exciting type 1 diabetes research taking place in her lab. Dr. Sneddon’s laboratory studies the underlying biology of the cellular microenvironment, including the cellular diversity and lineage relationships of the non-epithelial compartment of the pancreas in the context of organogenesis, adult organ function, and disease. Recently, Dr. Sneddon was just awarded the Helmholtz Young Investigator in Diabetes (HeIDi) award.
Monday Dec 14, 2020
Episode 43: Emrah Altindis, PhD, Assistant Professor, Boston College
Monday Dec 14, 2020
Monday Dec 14, 2020
In this episode, Emrah Altindis joins us to discuss his excellent publication, Parabacteroides distasonis insulin B:9-23 epitope mimic stimulates insulin specific T-cells and enhances type 1 diabetes in NOD mice. The main goal of Dr. Altindis' lab is to better understand the role of microbial mimicry mechanisms in human diseases and characterize these microbial proteins. In addition to the potential effects on metabolism and physiology of the host, these microbial mimickers have the potential to cause autoimmune diseases, including type 1 diabetes.
Thursday Dec 10, 2020
Thursday Dec 10, 2020
In this episode, Roland Eils and Luca Tosti join us to discuss their research in the type 1 diabetes space. Scientists from the BIH are coordinating an international project on the single-cell analysis of the human pancreas. The project is part of a global project- known as the Human Cell Atlas. Dr. Eils and Dr. Tosti provide us with information about the Human Cell Atlas.
Tuesday Dec 08, 2020
Tuesday Dec 08, 2020
In this episode, Per-Ola Carlsson joins us to discuss his latest research. Dr. Carlsson's work focuses on developing means to intervene with the development of type 1 diabetes mellitus and find treatment strategies to restore glucose homeostasis in patients with type 1 using cell therapy.
Want to read more about his work? Checkout a recent publication, Better HbA1c during the first years after diagnosis of type 1 diabetes is associated with residual C peptide 10 years later
Thursday Dec 03, 2020
Episode 40: Reena Singh, PhD, Research Fellow at The University of Sydney, Australia
Thursday Dec 03, 2020
Thursday Dec 03, 2020
In this episode, Reena Singh joins us to discuss her research and one of her recent publications titled, Enhanced Structure and Function of Stem Cell-Derived Beta-Like Cells Cultured on Extracellular Matrix. Dr. Singh is a developmental and stem cell biologist and her current area of research is to develop cell replacement therapy for people living with type 1 diabetes. Dr. Singh is working towards understanding the effect of beta cell niche on its structure and function and modifying the microenvironment to augment stem cell derived-beta cell function.
To learn more about Dr. Singh's and colleagues research visit Thorn's Lab website.
Tuesday Dec 01, 2020
Tuesday Dec 01, 2020
In this episode, Alex Kitching, Alex Spark, and Steven Lee join us to discuss vLUME technology, 3D Nanoimaging Platform and how it is applicable to type 1 diabetes researchers. vLUME is the world's first and only Virtual Reality solution for Super-resolution Microscopy.
Visualise, segment, and analyse in real-time your massive localization data at any scale.
Click the following link for a live demo of the technology:
Monday Nov 30, 2020
Monday Nov 30, 2020
In this episode, Jacob Hecksher-Sørensen joins us to discuss imaging diabetes using light sheet microscopy. Jacob walks us through some of the advantages of using this technology and provides us with a live demonstration from two previous experiments.
Checkout the full live demonstration following the link below:
Want to learn more about his published work? Follow the link below:
3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II
Thursday Nov 19, 2020
Thursday Nov 19, 2020
In this episode, Madina Makhmutova joins us to discuss her recent publication, Pancreatic beta cells communicate with vagal sensory neurons. Her research findings may have important implications for type 1 diabetes researchers.
To learn more about Dr. Makhmutova's research in the Islet-Caicedo Lab follow the link below:
Tuesday Nov 17, 2020
Tuesday Nov 17, 2020
In this episode, Andrew Sas joins us to discus his recent publication, A new neutrophil subset promotes CNS neuron survival and axon regeneration. Dr. Sas also discusses ongoing research in his lab and how the neutrophil may have the potential to mediate inflammation in other areas of the body, such as the pancreatic beta call under autoimmune attack in type 1 diabetes.
Listen to this episode to gain new insight and help address some important questions that were brought up and need further investigation.
Monday Nov 09, 2020
Monday Nov 09, 2020
In this episode, Calvin Carter and Sunny Huang join Monica Westley to discuss their new findings published Oct. 6 in Cell Metabolism, Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes, and new venture Geminii Health. Geminii Health is a medical device company that is pioneering a new wave of medicines and are building the NuWave, a wearable remote control to manage blood sugar.
Listen in as Dr. Carter and Dr. Huang discuss the pure serendipity of their findings.
Want to read more? Follow the link below:
Remote control of blood sugar: Electromagnetic fields treat diabetes in animal models